Table 2: Prediction of the diffusion mechanism based on the calculated release exponent values. | |
Drug release mechanism |
Release exponent (n) |
Case I transport (Fickian diffusion) |
n ≤ 0.5 |
Anamolous diffusion (non Fickian or coupled diffusion) |
0.5 < n < 1.0 |
Case II transport (Zero order) |
n = 1.0 |